关于 | Qiuyuan HUANG

高分子系统设计研究室

物质创成科学领域

奈良先端科学技术大学院大学

〒630-0192 奈良县生驹市高山町8916-5

我是 HUANG Qiuyuan，奈良先端科学技术大学院大学（NAIST）物质创成科学领域・高分子系统设计研究室特任助教。研究方向为生物可降解塑料、酶包埋材料、绝干与高温条件下的酶稳定性，以及高分子合成化学。

目前在 NAIST 的研究

我在 NAIST 所属于「自律的研究強化・社会実装（ARWIT）システムの構築と共有」（自主研究强化与社会实装 ARWIT 体系的构建与共享），这是 NAIST 在日本文部科学省「地域中核・特色ある研究大学強化促進事業（J-PEAKS）」下的战略之一，目标是把基础研究、数据利用与社会实装贯通起来。

酶包埋这条路线能否成立，取决于酶能否扛住塑料实际加工时的温度。因此我目前的研究集中在绝干状态的酶在受热时究竟发生了什么。在日本学术振兴会科研费「若手研究」（25K21401，2025–2027年度，研究代表者）的资助下，我正在解析绝干状态的酶在加热过程中发生的副反应与分子结构变化，并开发抑制这些变化的方法——这是设计更耐热的酶包埋材料的基础。

此前在东京大学的工作

我在东京大学大学院农学生命科学研究科取得博士学位，研究方向为生物可降解高分子。此后在该校先后担任特任研究员与特任助教，于2026年3月起就任现职。

关于在深海海底发生生物降解的酶包埋聚酯的研究，是在东京大学期间完成的，深海投放试验与海洋研究开发机构（JAMSTEC）合作开展。成果于2026年10月发表在 Nature，同时配有一篇 Research Briefing。

我希望通过开发可持续材料，为环境友好型高分子、生物可降解塑料以及酶包埋高分子体系这些领域做出贡献。

近期动态

Oct 21, 2026	Our paper “Enzyme-embedded polyesters for accelerated biodegradation in the deep sea” is published in Nature, accompanied by a Research Briefing.

代表性论文

Enzyme-embedded polyesters for accelerated biodegradation in the deep sea

QiuYuan Huang, Noriko Iida, Noriyuki Isobe, and 8 more authors

Nature, 2026

Bib HTML

@article{huang2026deepsea,
  title = {Enzyme-embedded polyesters for accelerated biodegradation in the deep sea},
  author = {Huang, QiuYuan and Iida, Noriko and Isobe, Noriyuki and Kabe, Taizo and Omura, Taku and Ilangovan, Manikandan and Kimura, Satoshi and Seok, Jin Ho and Nomaki, Hidetaka and Kasuya, Ken-ichi and Iwata, Tadahisa},
  journal = {Nature},
  year = {2026},
  doi = {10.1038/s41586-026-11192-1},
  publisher = {Nature Publishing Group}
}

The Next Frontier in Biodegradable Plastics: Enzyme-Embedding Biodegradable Polymers

QiuYuan Huang, Satoshi Kimura, and Tadahisa Iwata

Biomacromolecules, 2026

Bib

@article{huang2026frontier,
  title = {The Next Frontier in Biodegradable Plastics: Enzyme-Embedding Biodegradable Polymers},
  author = {Huang, QiuYuan and Kimura, Satoshi and Iwata, Tadahisa},
  journal = {Biomacromolecules},
  volume = {27},
  number = {5},
  pages = {2998},
  year = {2026},
  publisher = {American Chemical Society}
}

Exploring mechanisms and stabilization of anhydrous state cutinases: Toward sustainable high-temperature applications of enzyme

Qiuyuan Huang, Satoshi Kimura, and Tadahisa Iwata

Polymer Degradation and Stability, 2025

Bib

@article{huang2025mechanisms,
  title = {Exploring mechanisms and stabilization of anhydrous state cutinases: Toward sustainable high-temperature applications of enzyme},
  author = {Huang, Qiuyuan and Kimura, Satoshi and Iwata, Tadahisa},
  journal = {Polymer Degradation and Stability},
  volume = {240},
  pages = {111517},
  year = {2025},
  publisher = {Elsevier}
}

Improvement of Marine Biodegradability and Mechanical Properties of Poly(D-lactide) Films by Embedment of Poly(ethylene glycol)-Modified (PEGylated) Enzymes

QiuYuan Huang, Satoshi Kimura, and Tadahisa Iwata

ACS Sustainable Chemistry & Engineering, 2024

Bib

@article{huang2024improvement,
  title = {Improvement of Marine Biodegradability and Mechanical Properties of Poly(D-lactide) Films by Embedment of Poly(ethylene glycol)-Modified (PEGylated) Enzymes},
  author = {Huang, QiuYuan and Kimura, Satoshi and Iwata, Tadahisa},
  journal = {ACS Sustainable Chemistry \& Engineering},
  volume = {12},
  number = {31},
  pages = {11674--11682},
  year = {2024},
  publisher = {American Chemical Society},
}

Development of self-degradable aliphatic polyesters by embedding lipases via melt extrusion

QiuYuan Huang, Satoshi Kimura, and Tadahisa Iwata

Polymer Degradation and Stability, 2021

Bib

@article{huang2021development,
  title = {Development of self-degradable aliphatic polyesters by embedding lipases via melt extrusion},
  author = {Huang, QiuYuan and Kimura, Satoshi and Iwata, Tadahisa},
  journal = {Polymer Degradation and Stability},
  volume = {190},
  pages = {109647},
  year = {2021},
  publisher = {Elsevier}
}

Enzymatic self-biodegradation of poly (l-lactic acid) films by embedded heat-treated and immobilized proteinase K

QiuYuan Huang, Masatoshi Hiyama, Taizo Kabe, and 2 more authors

Biomacromolecules, 2020

Bib

@article{huang2020enzymatic,
  title = {Enzymatic self-biodegradation of poly (l-lactic acid) films by embedded heat-treated and immobilized proteinase K},
  author = {Huang, QiuYuan and Hiyama, Masatoshi and Kabe, Taizo and Kimura, Satoshi and Iwata, Tadahisa},
  journal = {Biomacromolecules},
  volume = {21},
  number = {8},
  pages = {3301--3307},
  year = {2020},
  publisher = {American Chemical Society},
}